Shakespeare? It’s in the DNA


Are you old enough to remember when floppy disks were actually floppy? Or maybe when disks were 3″ wide? (Yes, kids, that’s what that little icon to “save” your work to your hard drives and flash drives represents, a hard little disk that held approximately two Word files or a half a dozen pictures (but not at the same time).

Maybe you think data storage has reached its pinnacle. It is rather startling to realize you carry more technology in your pocket on your smart phone than was available for the moon landing (but with considerably less LOL cats).  But when you understand that there is now over one trillion gigabytes of information in the world, not even the iPhone 204 can keep up with that pace. (Here’s what 10 trillion gigabytes looks like in numbers: 10,000,000,000,000,000,000,000…. ten plus twenty one zeroes).

Every method of storage we have thus far employed has had long-term storage problems. CDs and DVDs scratch and wear out, as do magnetic tapes. But what about DNA, nature’s storage system? DNA is compact and durable. We can extract DNA information from bones that are millions of years old.

It sounds like science fiction, but it’s actually science-in-action. Nick Goldman heads up a research team at European Bioinformatics Institute in the U.K. Goldman and his fellow scientists are studying DNA data storage and Goldman has written a paper on the process which appeared  in the journal Nature last week.

In an interview with Ira Flatow on NPR’s “Science Friday,” Goldman explains that DNA utilizes a storage system much like computers use ones and zeroes so “[w]e wrote a computer program that embodied a code that would convert the zeros and ones from a hard disk drive into the letters that we use to represent DNA, and then we – our collaborators in California  - were able to actually synthesize physical DNA.”

Once the scientists realized this was possible, they decided what they would first try to encode and store:

[W]e chose a photograph of our own institute because we’re sort of self-publicists at heart, I guess, and an excerpt from Martin Luther King’s speech “I Have a Dream,” all of Shakespeare’s sonnets and a PDF that contained in fact the paper, the scientific paper by Watson and Crick that first described the structure of DNA itself.

All of this information, Golman says, is saved  on the equivalent of a speck of dust. How large of an area would contain all 10 trillion gigabytes of the world’s information? It would “fit in the back of a station wagon.”


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